RNF2 anticorps (AA 1-336)

N° du produit ABIN7599286

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RNF2 anticorps (AA 1-336) (ABIN7599286)

Antigène: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RNF2 anticorps

Épitope: AA 1-336

Fonction: Anti-RING2/RING1B/RNF2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-RING2/RING1B/RNF2 Antibody Picoband® (ABIN7599286). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RING2/RING1B/RNF2 recombinant protein (Position: M1-K336).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: RNF2 ring finger protein 2". 2. Lee SJ, Choi JY, Sung YM, Park H, Rhim H, Kang S (August 2001). "E3 ligase activity of RING finger proteins that interact with Hip-2, a human ubiquitin-conjugating enzyme". FEBS Lett 503 (1): 61-4. 3. Tuckfield, Annabel, Clouston David R, Wilanowski Tomasz M, Zhao Lin-Lin, Cunningham John M, Jane Stephen M (March 2002). "Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors". Mol. Cell. Biol. (United States) 22 (6): 1936-46.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur RNF2

Antigène: RNF2 (Ring Finger Protein 2 (RNF2))

Autre désignation: RNF2

Sujet:

Synonyms: Vinculin, Metavinculin, MV, VCL

Tissue Specificity: Metavinculin is muscle-specific.

Background: E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Poids moléculaire: 38 kDa

ID gène: 6045

UniProt: Q99496